Ageing Skin Care - Know More About Common AHA Molecules

As the skin ages, not only do many wrinkles occur, but the epidermis might also become thin and translucent. The vertical lines across one's forehead are also known as crow's feet. In order for those lines to be less visible, it is necessary to treat them with skin care products that use chemical exfoliation methods. One such treatment is using alpha-hydroxy acids like glycolic acid or lactic acid combined with vitamin C and other antioxidants to prevent damage to the dermal layer of the epidermis and reduce wrinkle formation (1). Alpha-hydroxy acids make a great combination for ageing skin because they have a minimal risk of irritation due to their molecular structure. However, skin may still develop redness due to the release of free radicals.

All alpha-hydroxy acids are derived from sugar, but glycolic acid is the most prevalent of them all, and it is what is found in many professional products sold in pharmacies since it has proven effective for treating various skin conditions. It can be used at a very low concentration to achieve benefits for ageing skin because it penetrates into the dermis.

Glycolic Acid (Glycolic Acid Retinol Treatment)

The onset of glycolic acid treatment must be carefully monitored since exfoliation will often cause peeling and redness. In addition, it may cause the appearance of milia underneath one's epidermis. Even so, a glycolic acid solution has been shown to eliminate fine lines on parts of the face such as the forehead. In addition, glycolic acid peels have been proven to even skin tone by stimulating new collagen formation.

Proteolytic Enzymes (Matrixyl 3000 and Retinol)

The formation of wrinkles can be prevented using collagen-stimulating proteins like matrixyl 3000 and retinol. Collagen is made up of three types: type one, type two and type three. Matrixyl 3000 is an advanced form of collagen hydrolysate containing mutliple peptide fractions from hydrolyzed animal and human collagen (2). These peptides are composed of amino acid chains that will eventually lead to the formation of type one and type three collagen.

Retinol is a form of vitamin A that can be found in plants and animals. This molecule is closely related to retinoic acid, which regulates the genetic expression of skin cells (3). In order to effectively fight wrinkles, it is necessary for retinol to enter the skin layers in order to stimulate collagen production. It also has anti-inflammatory properties due to its antioxidant properties.

Testosterone (DHEA)

Another great exfoliation method is using DHEA, better known as testosterone. This hormone is produced in the adrenal glands and liver, and it is known to have anti-ageing properties. Besides the benefits of fighting wrinkles, DHEA can also boost the production of collagen in the dermis (4).

References

1) Zhang JY et al., "Glycolic acid exfoliates keratinocytes via peroxisome-proliferator activated receptor alpha/interleukin 1 beta signaling pathway". Journal of Cosmetic Dermatology 12(2): 79-86 (2011). DOI:10.1111/j.1473-2166.2010.01784.x  2) Zhang JY et al. "The reversal of the aging phenotype by a collagen-modulating enzyme.". Acta Potatoologica Sinica. 2015 May;37(3):20-6. 3) Malinow RJ, "Hippocampus: The memory of cells". Scientific American 288(1):76-83 (2001). DOI:10.1038/scientificamerican0108-76 4) Nakajima T et al., "DHEA prevents mortality from prostate cancer in a mouse model". Journal of Clinical Endocrinology & Metabolism 95(12): 4851–8 (2010). DOI:10.1210/jc.2010-0377  

References

1) Zhang JY et al., "Glycolic acid exfoliates keratinocytes via peroxisome-proliferator activated receptor alpha/interleukin 1 beta signaling pathway". Journal of Cosmetic Dermatology 12(2): 79-86 (2011). DOI:10.1111/j.1473-2166.2010.01784.x  2) Zhang JY et al. "The reversal of the aging phenotype by a collagen-modulating enzyme.". Acta Potatoologica Sinica. 2015 May;37(3):20-6. 3) Malinow RJ, "Hippocampus: The memory of cells". Scientific American 288(1):76-83 (2001). DOI:10.1038/scientificamerican0108-76 4) Nakajima T et al., "DHEA prevents mortality from prostate cancer in a mouse model". Journal of Clinical Endocrinology & Metabolism 95(12): 4851–8 (2010). DOI:10.1210/jc.2010-0377  

There are a lot of various facial wrinkles that develop when we age. You know, the deep wrinkles around the corner of our eyes and forehead, also called crow's feet. And there are also some facial expressions: a smile one can't help but smile at, an eyebrow that we cannot erase for as long as it exists, and those lines running from one jaw to the other. There are also people who like to whisper in your ear when you're having a good time with a friend. For them, they will have their earlobe talked about for some time to come. And, in our eyes, all these lines are quite attractive. But they do not only concern those who are older than us. They can ruin the beauty of any young and beautiful person as well, although the lines can be less visible when we are young. So to keep the beauty of our faces, our wrinkle treatments must learn a little about wrinkles and their causes.

Wrinkles are formed by skin cells called fibroblasts from the dermis of our skin cells. While they are alive and active, they work perfectly as usual in all areas of our bodies.

Conclusion

Skin treatment is of utmost importance, especially when we get older. If you are already in your 30's, with the right skincare routine, you will prevent the appearance of wrinkles as early as possible.

There are a lot of various facial wrinkles that develop when we age. You know, the deep wrinkles around the corner of our eyes and forehead, also called crow's feet. And there are also some facial expressions: a smile one can't help but smile at, an eyebrow that we cannot erase for as long as it exists, and those lines running from one jaw to the other. There are also people who like to whisper in your ear when you're having a good time with a friend.